Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Laboratorios Poen
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Older than 18 years old
Patients with POAG and OH
PIO \< 20 mmHg
Under treatment with Dorzolamide + Timolol BAK preserved at least 6 month after
OSDI \> 13 \& one of these ocular signs (BUT \<6sec or Schirmer test \< 5 mm/5min or corneal staining positive)
Corneal thickness between 520-580 um.
You may not be if
Patient with severe respiratory diseases (asthma, COPD and other bronchospactic diseases).
Patient with cardiovascular diseases (Sinus Bradycardia, AV Block, Cardiac Failure, Cardiogenic Shock).
Severe renal impairment (CrCl \<30 mL/min)
Progressive diseases of the retina other than glaucoma
Inflammation and/or infecctions active
Ocular surface syndrome other than Ocular Surface disease
Eyelid disorder
Systemic adminsitration of Betablockers or carbonic anhydrase inhibitors
Patient that requires another antigluacomatous eye drop other than fixed combination of Dorzolamide/Timolol
Patients who use regularly lubricant eye drops
Patient who use regularly contact lenses
Patient with autoinmune diseases
Patients who underwent kerato-refractive laser procedures, cornea or corneal surface surgery, including, but not limited to, LASIK and PRK, within 6 months prior to the baseline visit.
Patients who have undergone a laser procedure or intraocular surgery or extraocular in either eye within 6 months prior to the baseline visit.
Patients with severe central visual field loss in either eye based onclinical judgment of the investigator. For the Humphrey and Octopus perimeters, the severe loss The visual field is defined as a sensitivity less than or equal to 10 dB in at least two(2) of the four (4) visual field test points closest to the fixation point
Patients with known hypersensitivity to any of the components of bothdrugs under study.
Pregnant or lactating women.
Women of childbearing age who are not using a contraceptive method.
Clareo Health | Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety
