Loading clinical trials...

The Evaluation of Balanced Salt Solution During Cataract Surgery | Clinical Trials | Clareo Health

COMPLETEDPHASE4

The Evaluation of Balanced Salt Solution During Cataract Surgery

NCT05853978•Adam Fedyk, MD, FACS

Summary

This study aims to identify if the use of BSS PLUS® Sterile Intraocular Irrigating Solution as an irrigation solution leads to improved corneal outcomes vs BSS® Sterile Irrigating Solution in more compromised corneas.

Eligibility

Age

22 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Adults, 22 years of age or older, with bilateral visually significant cataracts.
•2. Subjects with Fuch's Dystrophy that present with:
•1. nonconfluent and confluent guttata; and/or
•2. CCT \> 580 microns.
•3. Unremarkable systemic health but inclusive of controlled type II diabetes and hypertension
•4. Ability to comprehend and sign a statement of informed consent.
•5. Ability to complete all required postoperative visits.
•6. Willingness to use at least one medically acceptable form of birth control throughout the duration of study participation. (for female subjects of childbearing potential only).

Exclusion Criteria

•1. Planned implantation of multifocal intraocular lenses.
•2. Planned secondary procedure(s) to occur in conjunction with cataract surgery (i.e., goniotomy)
•3. History of severe dry eye.
•4. Retinal and retinal vascular pathologies, age-related macular degeneration
•5. Uncontrolled systematic diseases, including: hypertension, diabetes, systemic cardiovascular diseases and hematological diseases.
•6. Autoimmune disease such as rheumatoid arthritis.
•7. Female subjects of childbearing potential who are pregnant, nursing, planning a pregnancy, or not using a medically acceptable form of birth control.

Locations (1)

St. Louis Eye Institute

Town and Country, Missouri, United States

Key Dates

Start Date

April 17, 2023

Primary Completion Date

February 21, 2025

Completion Date

March 31, 2025

Last Updated

July 3, 2025

Enrollment

ACTUAL participants

Conditions

Fuchs DystrophyCataract

Interventions

BSS Plus

DRUG

BSS

DRUG

Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation

NCT06979752

Glaucoma, Open Angle, Pseudo-exfoliativeCataract

View study

RECRUITING

Assessment of a Hand-held Femtosecond Laser to Perform Anterior Capsulorhexis During Cataract Surgery (Post-market Study)

NCT07362043

Cataract Surgery

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 3, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

The Evaluation of Balanced Salt Solution During Cataract Surgery

Inclusion Criteria

Exclusion Criteria

Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation

Assessment of a Hand-held Femtosecond Laser to Perform Anterior Capsulorhexis During Cataract Surgery (Post-market Study)

IC-8 Apthera IOL New Enrollment Post Approval Study

HUD Surgical Guidance for Toric Alignment

PRO-232 in Patients Subjected to Cataract Surgery

Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery