Finding studies
Finding studies
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Lead
Robert Bok, MD, PhD
With
PRIMARY OBJECTIVES: I. To define the most appropriate imaging parameters for obtaining hyperpolarized 13C-aKG from participants with IDH mutant glioma. II. To assess the safety and feasibility of hyperpolarized 13C-aKG magnetic resonance (MR) metabolic imaging as a new and unique tool for evaluating tumor burden in participants with IDH mutant glioma. OUTLINE: Participants will be assigned to one of 2 cohorts: COHORT 1: Participants with IDH mutant glioma for sequence development. COHORT 2: Participants with recurrent IDH mutant glioma before receiving surgical resection. This imaging study will involve one MR scan with the administration of HP 13C-aKG and will receive a follow-up phone call within 1-7 days post-study to assess for late adverse events.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted