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EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD

NCT05850143•DR. MOHAMMAD ALI ARIF

Summary

In this Study i'll compare the effectiveness of two drugs used in acute exacerbation of asthma by their sideffects, complaince and improvement in the PRAM score. The better one would be adapted in our clinical practice.

Eligibility

Age

2 - 12 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•i.Ages 2 to 12years ii. Previous history of asthma as diagnosed by a physician. iii. Presentation with acute exacerbation of asthma with symptoms of cough, wheeze, dyspnoea and oxygen saturation of less than 95% and with PRAM score of more than or equal to 6

Exclusion Criteria

•i.Critical or life-threatening asthma i.e. patient with silent chest, cyanosis, drowsy, unable to verbalize, marked tachycardia and respiratory distress. ii.Known TB exposure iii.Fever more than 39. 5°C iv.Use of corticosteroids in previous 4 weeks v.Significant co-morbid disease: lung, cardiac, immune, liver, endocrine, neurological or psychiatric

Locations (1)

Asim Nawaz Niazi

Islamabad, Pakistan

Key Dates

Start Date

January 26, 2019

Primary Completion Date

December 26, 2023

Completion Date

December 26, 2023

Last Updated

May 9, 2023

Enrollment

192

ESTIMATED participants

Conditions

Asthma in Children

Interventions

Dexamethasone

DRUG

Prednisolone

DRUG

ASMact: Study on Management of Bronchial Asthma

NCT07412769

Asthma AcuteAsthma Childhood+2 more

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RECRUITINGNA

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

NCT06003569

Asthma in Children

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RECRUITINGPHASE2

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 9, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD

Inclusion Criteria

Exclusion Criteria

ASMact: Study on Management of Bronchial Asthma

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)

Omalizumab Before Onset of Exacerbations