STUDY DESIGN:
* This protocol is a single-center, single-cohort, bioresearch study enrolling up to 8 participants. The cohort is as follows:
* Cohort 1: Colorectal Cancer: (n=8)
* The study will enroll participants per the eligibility criteria.
* Participants will have 2 scheduled at-home stool self-collections at the time points specified in section 4.0 and complete a questionnaire by telephone contact (see section 11.0 for details). The biospecimens collected from participants on this study are stool samples.
* Confirmation of eligibility and medical record review by a member of the study staff will be completed for participants of the disease cohort before they are considered fully enrolled.