Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The Methodist Hospital Research Institute
Age
60–86
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of probable Alzheimer disease according to National Institute on Aging-Alzheimer's Association (NIA-AA) criteria13.
Male or female age 60 to 86 years
Clinical dementia rating scale of 1
Total bilirubin less than or equal to 1.5mg/dL
Alanine aminotransferase level (ALT) less than or equal to five times normal, albumin greater than or equal to 3.0gm/dL
Serum creatinine less than 1.5 mg/dL
English language speaking
A family member or caretaker who is expected to be consistently available, administer study drug and attend study visits throughout the study.
You may not be if
Serious, active bacterial, fungal or viral infection
Severe pulmonary dysfunction. FEV1 and FVC less than 40% of predicted (or 3 SD below normal) at baseline, If a pulmonary function test is clinically indicated. Hx of intubation for \>72 hours.
Severe cardiac dysfunction defined as left ventricular ejection fraction \<40% if an echocardiogram is medically indicated to clarify ongoing symptoms or EKG findings.; a history of non-controlled cardiac arrhythmias; history of cardiac tamponade; Unstable angina or MI in the last 3 months
Hypersensitivity or allergy to IL-2
Bowel ischemia/perforation, GI bleeding requiring surgery
Resistant seizures, history of coma or toxic psychosis lasting \>48 hours
Patients with White Blood Count (WBC) \<4,000/mm3; platelets \<100,000/mm3; hematocrit (HCT) \<30%.
