Loading clinical trials...

Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery | Clinical Trials | Clareo Health

COMPLETEDNA

Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery

Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients After Cardiac Surgery With Cardiac Pulmonary Bypass. Comparison of Propofol-based, Dexmedetomidine-based Sedation or Their Combination.

NCT05809518•Anesthesia Research Group UA

View on ClinicalTrials.gov

Summary

Preoperative, intraoperative and postoperative management of the patient are some of the main stages that can affect the hospital LOS and ICU LOS. Experience on the evidence-based approach and the progressive guidelines implementation of recommendations, the issue of the choice of drugs for sedation in the family and their impact on the length of stay in the intensive care unit and the length of hospitalization remain unsolved.

Detailed Description

Optimization of sedation regimes can become one of the factors that will help to reduce the length of hospital and ICU stay. The purpose of the study is to track is there a relationship between the drug for sedation and the length of stay of patients in the intensive care unit and in hospital treatment.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Multi vascular lesions of the coronary arteries according to coronary angiography;
•Heart valve damage was confirmed by heart ultrasound, which is subject to surgical correction (aortic stenosis of III degree with a gradient on the aortic valve of more than 42 mmHg, aortic insufficiency III, mitral valve stenosis II-III, mitral regurgitation II-III)
•Patient consent to participate in the study;
•Women who have a negative pregnancy test and use effective contraception throughout the study and for 3 weeks after its completion, or women who are unable to have children (women who have undergone a hysterectomy (removal of the uterus) or tubal ligation, women with a clinical diagnosis of infertility) or are menopausal for more than 1 year (absence of menstruation for at least 12 months). Adequate methods of contraception include: surgical sterilization, double barrier method of contraception, local contraception;

Exclusion Criteria

•Refusal to participate;
•Hypersensitivity to propofol, dexmedetomidine;
•Prolonged mechanical ventilation in case of surgical complications (bleeding, inadequate perfusion of the myocardium);
•Occurred ischemic stroke;
•History of the ischemic stroke;
•History of the neurodegenerative diseases;
•History of the mental disorders;
•Use of neuroleptics, antidepressants for the last 5 years;
•History of the cardiac surgery in the past;
•Patients with chronic pulmonary disease (GOLD 3-4)
+10 more criteria

Locations (1)

Medical Network Dobrobut

Kyiv, Ukraine

Key Dates

Start Date

January 1, 2017

Primary Completion Date

February 15, 2018

Completion Date

December 31, 2019

Last Updated

April 12, 2023

Enrollment

194

ACTUAL participants

Conditions

Sedation Complication

Interventions

Propofol injection

DRUG

Dexmedetomidine injection

DRUG

Dexmedetomidine and Propofol

DRUG

Validation of a Processed EEG Device for Monitoring Sedation in PICU

NCT05969483

Sedation Complication

View study

RECRUITINGNA

Effect of Goal-directed Analgesia and Sedation Using EEG Derived QCON/qNOX in ICU Patients

NCT06769308

Sedation ComplicationMechanical Ventilation Complication

View study

ACTIVE_NOT_RECRUITINGNA

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 12, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery

Inclusion Criteria

Exclusion Criteria

Validation of a Processed EEG Device for Monitoring Sedation in PICU

Effect of Goal-directed Analgesia and Sedation Using EEG Derived QCON/qNOX in ICU Patients

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19

Assessment of Sedation Depth Using Processed EEG in ICU Patients With ARDS Receiving Neuromuscular Blockade: A Prospective Observational Study"

Ventilatory Effects of THRIVE During EBUS