Weight stable (±3kg for greater than or equal to about 2 months)
No regularly planned exercise/physical activity
Women must have regularly occurring menses and must be premenopausal
You may not be if
EKG abnormalities
Evidence/history of cardiovascular disease, diabetes or other metabolic disease
Medications known to affect lipid or glucose metabolism
Pregnant or lactating
Tobacco or e-cigarette use
Prior experience of hypersensitivity to insulin, human albumin, and potassium chloride injection.
Allergies/hypersensitivity to local anesthetics of the amide type (e.g., lidocaine)
History of hyperkalemia or potential for developing hyperkalemia (including but not limited to taking drugs that may induce hyperkalemia such as cardiac glycosides or potassium sparing diuretics)
Clareo Health | Metabolic Adaptations to Weight Loss With and Without Exercise
