Clareo Health | Pregnancy-associated Progression of Chronic Kidney Disease: A Study Protocol for the Development and Validation of a Clinical Predictive Tool
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Keep this study
Lead
King's College London
The aim of this study is to develop and validate a tool that estimates the degree of pregnancy-associated progression of renal disease in women with CKD and pregnancy outcomes in an international multicentre cohort study. Two prediction models will be developed to estimate the likelihood of both outcomes. The models will be developed and internally validated in one cohort in the United Kingdom and then externally validated using four international datasets.
Age
18–50
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Women with an estimated Glomerular Filtration Rate (eGFR) using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) without ethnicity adjustment, less than 90mls/min/1.73m2 within 24 months pre-conception will be included
You may not be if
Women established on dialysis at time of conception
Multi-fetal pregnancies
Known inpatient eGFR measurement
No preconception eGFR within 24 months will be excluded.
