Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Exeter
With
U.S. Highbush Blueberry Council
Royal Devon and Exeter NHS Foundation Trust
Age
40–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Participants capable of giving informed consent
Sex: Male and female
Age: \> 40 years - Those under 40 are more likely to have an undiagnosed secondary cause of osteoarthritis
BMI: \> 18 kg/m2
Listed to have a total knee replacement for osteoarthritis
Participants are permitted to participate in other ongoing surgical intervention studies, as long as these are not trials of a dietary supplement or a medication.
You may not be if
Those who have received intravenous or oral immunosuppressant medications in past 2 years
Those who have had intra-articular steroid injection in 6 months preceding surgery.
Some secondary causes of osteoarthritis (mechanistic confounders that are likely to influence tissue inflammation measures:
Known congenital joint disorders
Other inflammatory arthritis e.g. rheumatoid arthritis
Avascular necrosis, infectious arthritis
Paget disease
Osteopetrosis
Osteochondritis dissecans
Hemochromatosis
Wilson's disease
Hemoglobinopathy
Ehlers-Danlos syndrome
Marfan syndrome
Acromegaly
Those typically consuming more than eight 80 g portions (or juice equivalent) of blueberries, blackberries, strawberries, raspberries, blackcurrants, pomegranate or cherries per week
Those with a known fruit allergy, for which they carry an adrenaline auto-injector or have required anti-histamine, adrenaline, glucocorticoid or beta-agonist treatment.
Those who cannot adequately understand verbal explanations or written information given in English
Clareo Health | Dietary Supplementation With Blueberry in OA
