Probiotic Supplementation Reduces Gastrointestinal Symptoms During the Therapy and Improves Therapeutic Response in AL Amyloidosis

Exclusion Criteria

• •Received antibiotics for 3 consecutive days and on in the past 2 months prior to the enrollment
• •Had history of probiotics, prebiotics, immunosuppressants, hormones, and other medications use in the past 3 months that influence the Gastrointestinal Microbiome
• •Had other underlying diseases（malignancy or immune system diseases, etc.）
• •Had history of clearly diagnosed chronic gastrointestinal disease
• •Secondary AL amyloidosis or local AL amyloidosis
• •Other conditions the researcher judged unsuitable for enrollment