Use of immunosuppressants

Congenital or acquired immunodeficiency (eg, history of HIV infection, hematological disease, current malignancy, or others)

Chronic condition that may significantly interfere with the immune response in the opinion of the investigator

History of Covid-19 within 16 weeks before study vaccination

Previous pneumococcal vaccination

Contraindication against any ingredient of the NVX or the PCV20 vaccine

Concomitant Administration of the Novavax Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years