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A Phase II Study of Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Patients With Gastric Cancer and Limited Peritoneal Metastasis: ROBO-CHIP Trial
This phase II clinical trial tests how well robotic cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) in treating patients with gastric cancer that has spread to the tissue that lines the wall of the abdominal cavity (peritoneum). Gastric cancer is the third leading cause of cancer related deaths worldwide and peritoneal metastasis are found in 30% of patients at time of diagnosis. Patients with peritoneal metastasis have poor survival rates. Traditional surgery is done with a large incision and has a high complication rate and longer hospital stays. Robot assisted (robotic) cytoreduction is a surgical option that uses small incisions and there is less risk of complications. HIPEC involves infusing heated chemotherapy into the abdominal cavity during surgery. Robotic cytoreduction together with HIPEC may improve recovery and decrease complications after surgery.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Start Date
April 20, 2023
Primary Completion Date
March 25, 2026
Completion Date
March 31, 2028
Last Updated
February 25, 2026
40
ESTIMATED participants
Cisplatin
DRUG
Computed Tomography
PROCEDURE
Gastrectomy
PROCEDURE
Magnetic Resonance Imaging
PROCEDURE
Positron Emission Tomography
PROCEDURE
Questionnaire Administration
OTHER
Paclitaxel
DRUG
Hyperthermic Intraperitoneal Chemotherapy
DRUG
Lead Sponsor
Mayo Clinic
NCT04704661
NCT06901531
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