Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mclean Hospital
With
University of California, San Francisco
Center for Medicinal Cannabis Research
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Documentation of newly diagnosed glioblastoma, evidenced by neuropathology report and based on World Health Organization (WHO) 2021 classification, and who are to undergo SOC (\~ 6 weeks of treatment) with radiation and temozolomide (patients using Optune may be included).
Written informed consent obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study.
Fluent in English.
Endorses at least moderate levels of anxiety (on the BAI or OASIS) at the screening visit
Stable medication/psychotherapy regimens for at least 1 month prior to starting the study (excluding new glioblastoma treatment-related medications or radiation).
Karnofsky Performance Scale (KPS) of 60 or higher.
You may not be if
Pregnant, breastfeeding, or unwilling to practice birth control during participation in the study.
Presence of a condition or abnormality that in the opinion of the Investigators would compromise the safety of the patient or the quality of the data.
Current substance use disorder, psychotic disorder, bipolar disorder, or eating disorder.
Current use of recreational cannabis, medical cannabis, or hemp-derived cannabinoid products more frequently than 1x/month; positive urine delta-9 tetrahydrocannabinol (THC) test.
Presence of a serious or unstable medical illness, including liver, kidney, or cardiovascular disease.
Current use of valproate (due to potential for drug-drug interactions).
Currently enrolled in other research studies or clinical trials involving therapeutic interventions.
Subjects with serum transaminase (ALT, AST, and total bilirubin) levels \>3 times upper limit of normal (UNL) \<24 hours prior to day 1 of treatment.
Contraindication to MRI such as non-MR conditional medical devices or ferrous retained foreign bodies.
