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Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer | Clinical Trials | Clareo Health

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Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer

Effect of Oxycodone Combined With Ultrasound Guided Thoracic Paravertebral Nerve Block on Postoperative Analgesia in Patients With Lung Cancer Undergoing Thoracoscopic Surgery

NCT05742256•Qianfoshan Hospital

View on ClinicalTrials.gov

Summary

In this study, the effect of oxycodone combined with ultrasound-guided paravertebral nerve block on the postoperative analgesic effect of thoracoscopic lung cancer was investigated, and the effect and reasonable dose of oxycodone were explored, which provided a reference for the clinical multimodal analgesia after thoracoscopic lung cancer surgery.

Eligibility

Age

60 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Male or female, age \> 60 years
•2. Patients undergoing thoracoscopic lobectomy
•3. ASA (American Academy of Anesthesiologists) Grades I-III
•4. There were no obvious abnormalities in heart, liver, and kidney function
•5. Sign the informed consent form for this clinical study

Exclusion Criteria

•1. History of oxycodone or sufentanil allergy
•2. Renal or hepatic dysfunction
•3. History of drug or alcohol abuse
•4. Psychiatric disorders: schizophrenia, epilepsy, Parkinson's disease, myasthenia gravis
•5. Those who have difficulty communicating due to coma, severe dementia, speech barrier, or those who cannot cooperate due to other diseases.
•6. People with head trauma or other brain diseases -

Key Dates

Start Date

March 1, 2023

Primary Completion Date

July 31, 2024

Completion Date

December 31, 2024

Last Updated

February 23, 2023

Enrollment

159

ESTIMATED participants

Conditions

Oxycodone

Interventions

Oxycodone 1mg/kg

DRUG

Oxycodone 1.5mg/kg

DRUG

Sufentanil

DRUG

Contacts

Pengcai Shi, Chief physician

CONTACT

13791126828 shipc1997@163.com

Effect of CYP2D6 on Perioperative Analgesia of Oxycodone in Elderly Patients

NCT07484867

PainPulmonary Nodules+1 more

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NOT_YET_RECRUITINGNA

Effect of Preventive Analgesia with Oxycodone and Parecoxib Sodium on the Chronification of Acute Post-operative Pain

NCT06721988

OxycodoneChronic Pain, Postoperative

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 23, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer

Inclusion Criteria

Exclusion Criteria

Effect of CYP2D6 on Perioperative Analgesia of Oxycodone in Elderly Patients

Effect of Preventive Analgesia with Oxycodone and Parecoxib Sodium on the Chronification of Acute Post-operative Pain

Application Software in Dosage Adjustment for Advanced Cancer Patients With Pain