Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Eli Lilly and Company
Age
60–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Gradual and progressive change in memory function reported by the participant or informant for ≥6 months.
A mini mental state examination (MMSE) score of 20 to 28 (inclusive) at screening.
Have an amyloid PET scan result from central read, consistent with the presence of amyloid pathology.
You may not be if
Have significant neurological disease affecting the central nervous system other than AD, that may affect cognition or ability to complete the study, including but not limited to, other dementias, serious infection of the brain, Parkinson's disease, multiple concussions, or epilepsy or recurrent seizures, except febrile childhood seizures.
Has current serious or unstable illnesses including cardiovascular, hepatic, renal, gastroenterologic, respiratory, endocrinologic, neurologic (other than AD), psychiatric, immunologic, or hematologic disease and other conditions that, in the investigator's opinion, could interfere with the analyses in this study.
A life expectancy of \<24 months.
Contraindication to MRI or PET scans
Have had prior treatment with a passive anti-amyloid immunotherapy.
Have a presence or history of malignant neoplasms within the past 5 years prior to Visit 1.
Exceptions:
non-metastatic basal- or squamous-cell skin cancer
Stage 0 non-invasive carcinoma of the cervix
Stage 0 non-invasive prostate cancer, or
other cancers with low risk of recurrence or spread
