Loading clinical trials...

Forced Oscillations Technique During a Metacholine Test in Children | Clinical Trials | Clareo Health

RECRUITINGNA

Forced Oscillations Technique During a Metacholine Test in Children

Interest of Forced Oscillations During a Methacholine Test in Children

NCT05734261•University Hospital, Montpellier

Summary

Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained

Eligibility

Age

6 - 16 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Age between 6 and 16 years
•FEV1 \> 60%
•Child referred to the pulmonary function test laboratory for a non-specific bronchial hyperactivity test with methacholine
•Child under treatment with inhaled corticosteroids stopped for at least 3 weeks
•Oral consent from the child and at least one of the legal representatives
•Child affiliated or benefiting from a social security plan

Exclusion Criteria

•Use of a short-acting beta-adrenergic bronchodilator within the last 6 hours or anticholinergic bronchodilator within the last 12 hours
•Use of a long-acting beta-adrenergic bronchodilator (licensed for use in children) in the past 36 hours
•Upper or lower respiratory tract infections within 3 weeks prior to inclusion
•Epilepsy under treatment
•Subject's participation in another interventional study that may alter respiratory function
•Patient unable to give consent, vulnerable

Locations (1)

CHU de Montpellier

Montpellier, France

Key Dates

Start Date

September 7, 2023

Primary Completion Date

February 15, 2026

Completion Date

December 30, 2026

Last Updated

September 13, 2023

Enrollment

112

ESTIMATED participants

Conditions

Asthma in Children

Interventions

Airway Oscillation System

PROCEDURE

Contacts

Stefan MATECKI, MD

CONTACT

+33 4 67 33 59 12 Stephan.matecki@umontpellier.fr

Anne REQUIRAND

CONTACT

a-requirand@chu-montpellier.fr

ASMact: Study on Management of Bronchial Asthma

NCT07412769

Asthma AcuteAsthma Childhood+2 more

View study

RECRUITINGNA

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

NCT06003569

Asthma in Children

View study

RECRUITINGPHASE2

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 13, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Forced Oscillations Technique During a Metacholine Test in Children

Inclusion Criteria

Exclusion Criteria

ASMact: Study on Management of Bronchial Asthma

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)

Omalizumab Before Onset of Exacerbations