Methods:
All patients will be subjected to the following:
1. Thorough medical history of the patients
2. Full clinical examination including:
1. General examination and vital signs.
2. Complete rheumatological examination.
3. SLE disease activity index SLEDAI (ref).
4. SLICC damage index (ref).
3. Routine investigations (complete blood picture, erythrocyte sedimentation rate and liver functions).
4. Renal investigations:
1. Kidney functions
2. Urine analysis
3. 24 hours protein in urine and/or A/C ratio
4. Renal biopsy if indicated.
5. ANA test.
6. ANA profile for the most common 19 autoantibodies by immunoblot.
Age
0–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patients diagnosed as SLE( Systemic lupus erythematosus )according to EULAR / ACE (European League Against Rheumatism /American College of Rheumatology )
2. Age juvenile SLE ( Systemic lupus erythematosus )was defined as a diagnosis below the age of 18 years, and those diagnosed between 19 and 50 years of age were classified as adult SLE ( Systemic lupus erythematosus ), late onset SLE was defined as a diagnosis at more than 50 years of age).
3. Patients with a disease duration of more than 6 months
You may not be if
1. Patients with had other autoimmune diseases, such as rheumatoid arthritis, systemic sclerosis, mixed connective tissue disease , overlap syndrome or primary Sjogren's syndrome ,but not secondary Sjogren's syndrome or secondary antiphospholipid syndrome .
2. Patients who are not willing to be involved in the study
Clareo Health | Comparison of Clinical and Serological Differences Among Juvenile, Adult, and Late-onset Systemic Lupus Erythematosus
