Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream

Exclusion Criteria

• •Interstitial cystitis or bladder pain syndrome, nephrolithiasis, genitourinary abnormalities, fistula, history of renal transplant or anatomic abnormality of the kidney
• •Fecal incontinence, intermittent catheterization or indwelling catheter, poorly controlled DM, urothelial cancer, estrogen-sensitive cancer including active breast cancer
• •Recent urologic surgery within 3 months
• •Inability to retain vaginal tablet (ex due to advanced prolapse, history of colpocleisis)
• •Other medical reasons that are deemed incompatible with vaginal estrogen treatment
• •Use of vaginal estrogen in the past 1 month- patients can be recruited after a 1 month wash-out period
• •Inability to follow up at clinic study site to give sample, for example due to transportation issues
• •Organ transplant patients
• •Patients on systemic hormone replacement therapy (HRT)