Age

Any age

Sex

MALE

Healthy volunteers

Not accepted

1. Diagnosed as prostate cancer pathologically by prostate biopsy
2. Evaluated as localized prostate cancer by imaging studies
3. Prostate volume\>70mL evaluated by transrectal ultrasonography or multi-parametric magnetic resonance imaging
4. Gleason score≤ 4+3=7
5. Preoperative PSA\<20ng/mL
6. Estimated survival\> 10 years；
7. Informed consent is obtained from the patient

1. The patient has received other therapy including radical radiotherapy, transurethral resection of the prostate, cryoablation, HIFU, etc.
2. Any contraindication of surgery or anaesthesia

Safety and Efficacy of Two-step Radical Prostatectomy