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OCT Eccentric Fixation and Amblyopia in Children | Clinical Trials | Clareo Health

RECRUITINGNA

OCT Eccentric Fixation and Amblyopia in Children

OCT Eccentric Fixation, Fixation Stability, and Amblyopia in Children

NCT05714449•State University of New York College of Optometry

Summary

The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.

Detailed Description

Aim 1. OCT EF changes with patching treatment at 12 weeks visit. Aim 2. OCT EF changes with foveation therapy.

Eligibility

Age

4 - 16 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines,
•2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic.
•* Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D;
•* strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery;
•* combined type included those who meet the criteria of both anisometropia and strabismus.
•* For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old.
•* For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.

Exclusion Criteria

•born before 32 weeks gestational age;
•neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;
•congenital or acquired macular pathology.

Locations (1)

SUNY College of Optometry

New York, New York, United States

Key Dates

Start Date

January 25, 2023

Primary Completion Date

January 24, 2025

Completion Date

January 24, 2026

Last Updated

April 23, 2024

Enrollment

ESTIMATED participants

Conditions

Amblyopia

Interventions

eye patch

DEVICE

After-image and MIT trainer

DEVICE

Contacts

Jingyun Wang, PhD

CONTACT

2129385759 jwang@sunyopt.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 23, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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OCT Eccentric Fixation and Amblyopia in Children

Inclusion Criteria

Exclusion Criteria

Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP). The Aim Of The Study Is To Evaluate Possible Beneficial Effects For Different Age Groups.

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

Patch-free Occlusion Therapy

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