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Music Intervention and Transcranial Electrical Stimulation for Treating Neurological Diseases
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress. Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Istituti Clinici Scientifici Maugeri
Bari, Ba, Italy
Start Date
September 1, 2022
Primary Completion Date
December 31, 2026
Completion Date
December 31, 2026
Last Updated
June 4, 2025
90
ESTIMATED participants
Combinatory effect of music stimulation and neurostimulation
OTHER
Lead Sponsor
Istituti Clinici Scientifici Maugeri SpA
Collaborators
NCT06258538
NCT07371455
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05093673