Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease.

Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease: Mortality and Dialysis Initiation, a Prospective Cohort Study.

NCT05705011•Grigore T. Popa University of Medicine and Pharmacy

View on ClinicalTrials.gov

Summary

This observational study explores the impact of cognitive impairment and frailty in older adults with advanced chronic kidney disease \]. The main question\[s\] it aims to answer are: * What determines the time to initiate dialysis? Cognitive impairment or frailty? * What does predict the time to death? Presence of frailty or cognitive impairment? * What does correlate strongly with time-low health-related quality of life? frailty or cognitive impairment?

Eligibility

Age

65 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients age 65 years or older.
•CKD stage 4 and 5 who were identified by two consecutive measurements of estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73 m2 separated by more than 3 months.

Exclusion Criteria

•Patients younger than 65 years old.
•Chronic kidney disease stages 1,2, and 3.
•Dialysis dependence
•History of kidney transplantation.
•Initial visit with the health care provider.
•Recent acute kidney injury.
•Patients who had been hospitalized for more than 2 months before the visit (because long hospitalization might affect the degree of frailty)
•Patients with myocardial infarction and cerebrovascular accident 3 months before the assessment
•Patients who are blind or with limb amputation.
•Patients who refuse to participate.

Locations (1)

University of Medicine and Pharmacy "Grigore T. Popa"

Iași, Romania

Key Dates

Start Date

March 1, 2019

Primary Completion Date

March 5, 2023

Completion Date

March 12, 2023

Last Updated

February 15, 2024

Enrollment

240

ACTUAL participants

Conditions

CKD Stage 4CKD Stage 5FrailtyCognitive Impairment

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 15, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease.

Inclusion Criteria

Exclusion Criteria

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