The goal of this project is to determine the feasibility of a specific home-based exercise intervention in reducing cancer-related fatigue (CRF) in breast cancer patients undergoing curative-intent chemotherapy. The outcome will be measured by using the FACIT Fatigue Scale, administered by using the Carevive PROmpt® platform.
Primary Objectives:
1. . To examine the feasibility of recruitment and retention of women undergoing treatment for breast cancer over the duration of the chemotherapy regimen.
2. To examine the adherence to the exercise regime for those in the intervention group and compare the retention rates between treatment and control groups
3. To compute the means and standard deviations (SD) of the FACIT responses over time in both groups for use in future power analyses to aid in the design of a futre hypothesis testing RCT.
Secondary Objectives:
1. To quantify the change over time in PRO-CTCAE derived symptoms and other PROs by computing means and SD.
2. To test for group differences in the trajectory of change over time in FACT using a Mixed Model repeated analysis
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Women with curative-intent breast cancer who plan to undergo at least 4 cycles of chemotherapy.
Age \> 18 years
ECOG performance score \< 3
English-speaking
with sufficient vision/hearing or family support
Coronary artery disease, if cleared by cardiologist
Subject must have smart phone, computer or tablet.
Willingness to be randomized
You may not be if
Medical or psychiatric conditions (beyond those related to breast cancer and its treatment) that would impair our ability to test study hypotheses (psychotic disorders, dementia, inability to give informed consent or follow instructions).
Patients with overt evidence of a psychiatric disorder.
Coronary artery disease, not cleared by cardiologist.
Contraindication to exercise.
Chronic fatigue syndrome.
Clareo Health | Evaluate Impact of Exercise Program on Fatigue in Breast Cancer During Chemotherapy
