An Observational Study Called FIRST-2.0 to Learn More About the Use of the Study Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Bayer
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Minimum of 12 months continuous enrolment in the EHR databases with medical and pharmacy coverage measured as continuously receiving medical care from health providers contributing to the EHR system.
No recorded prescription of finerenone prior to the index date.
Age 18 years or older as of the index date.
T2D diagnosis at any point before (and including) the index date using the same algorithms applicable to the specific data source as in previous studies of the FIRST program.
CKD stages 2-4 related to eligibility will be defined according to the presence of the following criteria at any point before (and including) the index date:
* A diagnosis code indicating CKD stage 2, 3, 4, or stage unspecified OR
* Two Urinary Albumin-to-Creatinine Ratio (ACR) test results ≥ 30 mg/g separated by at least 90 days and no more than 540 days OR
* Two different eGFR test results ≥ 15 mL/min/1.73 m\*2 AND \< 60 mL/min/1.73 m\*2 separated by at least 90 days and no more than 540 days.
You may not be if
Type 1 diabetes identified by appropriate algorithms in the data source
Kidney cancer on or before the index date
Kidney failure defined as:
* Two different eGFR test results \< 15 mL/min/1.73 m\*2 separated by at least 90 days and no more than 540 days
* Dependence on dialysis (at least 3 sessions over at least 90 days during the baseline period)
* A diagnosis code indicating kidney failure or CKD stage 5 (International Classification of Diseases, 10th Revision)
* Kidney transplant
Clareo Health | An Observational Study Called FIRST-2.0 to Learn More About the Use of the Study Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions
