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Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
China Medical University Hospital
Taichung, Taiwan
Start Date
August 27, 2021
Primary Completion Date
August 26, 2022
Completion Date
August 26, 2023
Last Updated
February 13, 2025
20
ACTUAL participants
Low Level Laser Therapy
DEVICE
Placebo
OTHER
Lead Sponsor
China Medical University Hospital
NCT06403033
NCT05766033
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View ClinicalTrials.gov Terms and ConditionsNCT05644119