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COMPLETEDNANCT05691205

Identifying Optimal PEEP After Lung Transplantation

Lung Transplantation (LuTX) is the curative treatment for selected patients with end-stage lung disease. Primary Graft Dysfunction (PGD), a specific form of respiratory failure occurring within the fi...

Lead sponsor: Policlinico Hospital•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Policlinico Hospital

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Recipient of LUTX
•Age \> 18 years
•Signed informed consent

Exclusion Criteria

•Age \< 18 years
•Already undergone LUTX
•Major hemodynamic instability along the 24 hours following LUTX: systolic arterial pressure \< 90 mmHg and/or heart rate \> 120 beat/min and/or high dose vasopressor requirement (norepinephrine \> 0.3 mcg/kg/min and/or epinephrine \> 0.2 mcg/kg/min and/or dobutamine \> 8mcg/kg/min)
•Documented post-LUTX endobronchial plasma leak requiring high levels of PEEP \> 15 cmH2O

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 2, 2025Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment47

Start dateJan 2023

Last updatedApr 2, 2025

Condition

Lung Transplant; Complications Primary Graft Dysfunction

Locations shown

Fondazione IRCCS Ca'Granda - Ospedale Maggiore Policlinico

Milan, Milan

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 2, 2025Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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