A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4)

Exclusion Criteria

• •1. Any disorder, except for conditions associated with haemophilia A, which in the investigator's opinion might jeopardise participant's safety or compliance with the protocol.
• •2. Participant who has discontinued or been withdrawn from studies NN7769-4513, NN7769-4514, NN7769-4516, or NN7769-4728.
• •3. Previous participation in this study. Participation is defined as signed informed consent.
• •4. Female who is pregnant, breast-feeding or intends to become pregnant.
• •5. Female of child-bearing potential and not using a highly effective contraceptive method (highly effective contraceptive measures or as required by local regulation or practice).
• •6. Participation (i.e., signed informed consent) in any interventional, clinical study (except from study NN7769-4513, NN7769-4514, NN7769-4516, or NN7769-4728) of an approved or non-approved investigational medicinal product.
• •7. Any planned major surgery, during part 1 of the study.
• •8. Mental incapacity, unwillingness to cooperate, or a language barrier precluding adequate understanding and cooperation.
• •Arm 3:
• •1. Known or suspected hypersensitivity to trial product or related products.
• •2. Previous participation in study 4532. Participation is defined as signed informed consent.
• •3. Participation (i.e., signed informed consent) in any interventional clinical study with receipt of the last dose within 6 months (or 5 half-lives of the investigational medicinal product, whichever is shorter) before planned enrolment.
• •4. Exposure to non-factor haemostatic products for bleeding prophylaxis within 6 months (or 5 half-lives of the medicinal product, whichever is shorter) before planned enrolment.
• •5. Known congenital or acquired coagulation disorders other than haemophilia A.
• •6. Other conditions (e.g., autoimmune disease) or laboratory abnormality that may increase the risk of bleeding or thrombosis, as evaluated by the investigator. Any disorder, except for conditions associated with haemophilia A, that in the investigator's opinion might jeopardise the participant's safety or compliance with the protocol.
• •7. Lack of adequate parental/legally acceptable representative (LAR) support to enter accurately and timely information regarding treatment and bleeding episodes into an (electronic) diary.
• •8. Previous or current treatment for thromboembolic disease (with the exception of previous catheter-associated thrombosis for which anti-thrombotic treatment is not currently ongoing) or signs of thromboembolic disease.
• •9. Any planned major surgery, during part 1 of Arm 3 (infant). For definition of major surgery.
• •10. Immune tolerance induction planned to take place after treatment initiation.
• •11. Hepatic dysfunction defined as AST and/or ALT greater than (\>) 3 times the upper limit of normal (ULN) combined with total bilirubin \>1.5 times the ULN.
• •12. Serum creatinine above 1.5 times the ULN.