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Efficacy of TTMPB in Adult Cardiac Surgery | Clinical Trials | Clareo Health

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UNKNOWNNANCT05681507

Efficacy of TTMPB in Adult Cardiac Surgery

The goal of this clinical trial is to compare the efficacy of Transversus Thoracic Muscle Plane Block (TTMPB) integrated in a modern multimodal analgesia protocol, following the ERAS® recommendations,...

Lead sponsor: Eric Albrecht•1 locations•View source on ClinicalTrials.gov

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Contacts

Valentina Rancati, Attending physician

CONTACT

0041 79 556 88 68 valentina.rancati@chuv.ch

Eric Albrecht, Attending physician

CONTACT

0041 21 314 20 07 eric.albrecht@chuv.ch

Sponsors

Lead Sponsor

Eric Albrecht

Age

18 - 100 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Direct informed consent as documented by signature
•Major adult (≥ 18 years old) with body weight ≥ 50 kg. For the record, fifty kilograms is the minimal weight to ensure that participants remain safely away from maximal doses of LA (3 mg/kg)
•Planned and primary cardiac surgery via a sternotomy approach
•Planned for ultra-fast-track procedure (i.e. postoperative extubation time of maximum two hours)

Exclusion Criteria

•Participation in another study with investigational drug within the 30 days preceding and during the present study
•Refusal and/or inability to understand or sign the informed consent
•Emergent cardiac surgery
•Previous cardiac surgery
•Known hypersensitivity or true allergy to bupivacaine and other amide-class LA
•Chronic pain history
•Substance abuse history
•Inability to follow the procedures of the study (e.g. due to language problems, psychological / psychiatric disorders, dementia)
•Clinically significant concomitant diseases: severe cardiac dysfunction (i.e. LVEF ≤ 35%); severe chronic obstructive pulmonary disease (i.e. FEV \< 50%); severe hepatic disease.
•Severe obesity (BMI \> 35kg/m2)

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 23, 2023Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment140

Start dateDec 2022

Last updatedJan 23, 2023

Condition

Acute Post Operative Pain

Locations shown

CHUVaudois

Lausanne, Canton of Vaud

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 23, 2023Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions