Humerus, femur, or tibia segmental defects requiring surgery
Evaluation and treatment at UCSD
Ages 18 year and older
Abiltiy to understand the content of the patient information/informed consent form
You may not be if
Any not medically managed severe systemic disease
Their doctor has decided that it is in the patient's best interest to receive a different method of repair
Their doctor has determined that the patient has a condition that would make them unsuitable for participation in the study
Pregnancy or women planning to conceive within the subject participation period (1 year) note: pregnancy will be self-reported and no test will be performed to test for it
Prisoner
Participation in any other pharmacologic or medicinal product study within the previous month that could influence the results of this study.