Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Nami Safai Haeri
With
The Claude D. Pepper Older Americans Independence Centers
National Institute on Aging (NIA)
Age
65–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Ambulatory adults age ≥65 years including those using assistive devices to maximize generalizability, if they have criteria for treating osteoporosis including:
1. Osteoporosis by axial bone density (spine, hip or forearm BMD T-score ≤-2.5 SD) or
2. A previous adult fragility fracture of the spine or hip or
3. Would be treated based on FRAX National Osteoporosis Foundation treatment thresholds of a 10-year risk of ≥ 20% for a major osteoporotic fracture or ≥ 3% for hip fracture using femoral neck BMD.
You may not be if
1. Patients with a calculated creatinine clearance \< 35 ml/min or
2. Who have a contraindication for bisphosphonates or denosumab or
3. Those who are scheduled for a tooth extraction to avoid jaw osteonecrosis or
4. Subjects with severe liver disease or
5. Those who have been on oral bisphosphonates for the past 1 year and intravenous bisphosphonates for the past 2 years prior to the study or
6. Men
Clareo Health | Muscle Impact of Treating Osteoporosis
