A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants

Exclusion Criteria

• •History of any significant illness or disorder.
• •History of stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs (uncomplicated appendectomy, hernia repair, and/or cholecystectomy will be allowed).
• •History or presence of:
• •1. additional risk factors for torsades de pointes (e.g., heart failure, hypokalemia, family history of long QT syndrome).
• •2. sick sinus syndrome, second or third degree atrioventricular block, myocardial infarction, pulmonary congestion, symptomatic or significant cardiac arrhythmia, prolonged QTcF interval, or clinically significant conduction abnormalities.
• •Clinically significant illness within 4 weeks prior to check in.
• •Participants with an inability to swallow tablets.