Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
With
United States Department of Defense
Clark Charitable Foundation Inc.
Age
1–26
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
1. STRATUM A
1. Eligibility Criteria
* aged 1 to \<26 years of age
* tumor must be located in the brain or adjacent to the brain including but not limited to nasopharynx, paranasal sinuses and orbit
* treatment must include radiation therapy (either proton or photon)
* patients must not have completed radiation therapy
You may not be if
* pregnancy
* patients who are not able to undergo neuro-cognitive testing, including children lacking English comprehension or children with premorbid neurological/neurodevelopmental disorders such as Down's syndrome or autism
2. STRATUM B
1. Eligibility Criteria
* diagnosed with a brain tumor at \<26 years of age
* received radiation to the brain as part of therapy
* time from radiation start to study enrollment is ≥ 2 years
* there has not been disease recurrence from time of most recent radiation treatment to study enrollment
* patients who are not able to undergo neuro-cognitive testing, including children lacking English comprehension or children with premorbid neurological/neurodevelopmental disorders such as Down's syndrome or autism
3. STRATUM C
1. Eligibility Criteria
* must be aged 5 to \<26 years of age
* must be able to complete research imaging without sedation
* must not have any major psychiatric, neurologic or medical diagnosis
Clareo Health | Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
