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Vaccine Immune Recovery After Leukemia | Clinical Trials | Clareo Health

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COMPLETEDNCT05622682

Vaccine Immune Recovery After Leukemia

This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children, adolescents, and young adults who recently completed treatment for acute...

Lead sponsor: Children's Hospital of Philadelphia•6 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Children's Hospital of Philadelphia

Collaborators

Merck Sharp & Dohme LLC

Age

3 - 31 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Children, adolescents, and young adults diagnosed with B or T ALL at age 12 months or older
•Completed ALL chemotherapy within the past three months or will complete ALL chemotherapy in the upcoming three months
•Three years of age or older at time of enrollment

Exclusion Criteria

•Diagnosis of infant ALL
•Evidence of disease relapse
•History of primary immunodeficiency (except related to Down Syndrome)
•History of a stem cell transplant or cellular immunotherapy
•History of prior malignancy or condition requiring chemotherapy other than for current ALL diagnosis

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 26, 2026Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment89

Start dateSep 2022

Last updatedJan 26, 2026

Condition

Acute Lymphoblastic Leukemia, Pediatric

Locations shown

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois

Helen DeVos Children's Hospital

Grand Rapids, Michigan

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 26, 2026Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions