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Hepatitis C virus is commona viral infection. Direct-acting antiviral (DAA) oral drugs has been used in treatment of HCVs. the effect of these drugs on male infertility is still under investigation.
Semen analysis will be done to male patients with HCV before and after treatment with DAA. The included men will take therapy for 3 months and HCV RNA titter will be evaluated. changes of seminal parameters will be recorded and analyzed.
Age
18 - 55 years
Sex
MALE
Healthy Volunteers
Yes
Faculty of Medicine, Benha University
Al Qalyūbīyah, Benha, Egypt
Benha Faculty of Medecine
Banhā, Egypt
Start Date
March 1, 2022
Primary Completion Date
November 25, 2022
Completion Date
December 31, 2022
Last Updated
February 8, 2023
200
ACTUAL participants
Sofosbuvir +daclatasvir+ simeprevir+Ribavirin
DRUG
Lead Sponsor
Benha University
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05653232