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COMPLETEDPhase 3NCT05615025

Influence of Sevoflurane and Propofol on Maximum Muscular Strength, Speed of Contraction and Relaxation

Many drugs have an influence on neuromuscular transmission. In clinical practice, neuromuscular blocking agents are commonly used, but even in the absence of neuromuscular blocking agents, anesthetic ...

Lead sponsor: Brugmann University Hospital•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Brugmann University Hospital

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients (male or female) from 18 - 80 years
•Scheduled for surgery without the use of neuromuscular blocking agents
•Health care insurance in Belgium
•Written informed consent

Exclusion Criteria

•Any pathology involving neuromuscular transmission
•Confirmed neuropathy of any origin
•Expected anesthesia duration \< 30 min
•Renal insufficiency defined as a glomerular filtration rate \< 40 mL/min/m2
•Hepatic insufficiency defined as an increase \> 1.5 \* normal value of hepatic enzymes
•Confirmed or suspected pregnancy
•Language barrier
•Any patient which will receive unplanned neuromuscular blocking agents during surgery
•Any history of personal or familial suspected malignant hyperthermia

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 10, 2023Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment48

Start dateJan 2023

Last updatedJul 10, 2023

Condition

Anesthesia, General Neuromuscular Transmission Disorders

Locations shown

CHU Brugmann

Brussels

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 10, 2023Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions