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Neurofeedback During Eating: A Novel Mechanistic Treatment for Bulimia Nervosa
The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using a wearable brain imaging device, functional near-infrared spectroscopy (fNIRS). The investigators will examine how this training may influence inhibitory control and BN symptoms.
The purpose of this study is to examine the effects of PFC neurofeedback during eating in women with bulimia nervosa (BN) using fNIRS. Specifically, the study aims 1) to demonstrate ventrolateral PFC (vlPFC) neurofeedback target engagement in women with BN using fNIRS; and 2) to link changes in PFC activation to changes in inhibitory control and eating-related symptoms. Data will be collected from women with BN who will be randomly assigned to one of two group conditions (real or sham-control neurofeedback during eating). Participation includes a phone screening assessment, psychodiagnostic assessment, one in-person evaluation, one neurofeedback session, behavioral tasks, online questionnaires before and after the neurofeedback session, and a remote follow-up assessment.
Age
18 - 45 years
Sex
FEMALE
Healthy Volunteers
No
Center for Computational Psychiatry at the Icahn School of Medicine at Mount Sinai
New York, New York, United States
Start Date
May 13, 2024
Primary Completion Date
December 1, 2027
Completion Date
December 1, 2027
Last Updated
January 30, 2026
30
ESTIMATED participants
Real fNIRS Neurofeedback
OTHER
Sham-Control fNIRS Neurofeedback
OTHER
Lead Sponsor
Icahn School of Medicine at Mount Sinai
NCT07478510
NCT05995496
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05304104