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Role of Trans-cranial Direct Current Stimulation in Appetite and Weight Control: A Prospective Randomized Study
To study the effects of transcranial direct current stimulation (tDCS) on weight and appetite.
1. To compare weight loss over one month in active tDCS group with sham tDCS group. The investigator will measure weight of every participants at the beginning of the study and one month after the last session of tDCS 2. To compare change in insulin sensitivity over one month in active tDCS group with sham tDCS group. The investigator will measure fasting insulin and glucose level, and calculate homeostatic model assessment-insulin resistance (HOMA-IR) 3. To compare change in cognitive performance as a response to food over one month in active tDCS group with sham tDCS group. The investigator will evaluate performance in a computerized task that measures executive functions under the presence of food (working memory, inhibitory control and a combination of both). The investigator will assess changes in accuracy and speed in the task under active tDCS versus sham tDCS. 4. To compare change in post-prandial glucose excursion and average meal counts per day. The investigator will use continuous glucose monitor to record the frequency and amplitude of glucose excursion.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
ECMC Ambulatory Center, 3rd Floor
Buffalo, New York, United States
Start Date
January 1, 2017
Primary Completion Date
October 25, 2022
Completion Date
October 25, 2022
Last Updated
January 30, 2024
4
ACTUAL participants
tDCS
DEVICE
Shame- No current
DEVICE
Lead Sponsor
University at Buffalo
Collaborators
NCT06989203
NCT07104383
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT06861790