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NOT_YET_RECRUITINGNA

Hypoxia and Heart Rate Variability

NCT05606406•University of Miami

Summary

The purpose of this study is to evaluate how variations in oxygen demands may change heart electrical activity in individuals with and without oxygen dependence.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy Participants
•Ability to provide consent
•Ability to provide consent
•Chronic respiratory condition resting Sat \< 95% off oxygen

Exclusion Criteria

•BMI \> 40 kg/m2
•Prevalent myocardial infarction, coronary revascularization, heart failure, and stroke
•Unstable medical conditions that may preclude enrollment in the protocol such as: uncontrolled angina and/or congestive heart failure, uncontrolled blood pressure or resistant hypertension, cancer, and active psychiatric disease (e.g., major depression)
•Nocturnal Hypoxemia
•BMI \> 40 kg/m2
•Prevalent myocardial infarction, coronary revascularization, heart failure, and stroke
•Unstable medical conditions that may preclude enrollment in the protocol such as: uncontrolled angina and/or congestive heart failure, uncontrolled blood pressure or resistant hypertension, severe chronic obstructive pulmonary disease, cancer, and active psychiatric disease (e.g., major depression)

Locations (1)

University of Miami

Miami, Florida, United States

Key Dates

Start Date

May 30, 2026

Primary Completion Date

December 30, 2027

Completion Date

December 30, 2027

Last Updated

February 5, 2026

Enrollment

ESTIMATED participants

Conditions

Pulmonary Disease, Chronic ObstructiveHypoxia

Interventions

Nocturnal Oxygen

OTHER

Contacts

Trishul Siddharthan, MD

CONTACT

305-243-6388 tsiddhar@miami.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 5, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Hypoxia and Heart Rate Variability

Inclusion Criteria

Exclusion Criteria

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Added Diagnostic Value of Point of Care Ultrasound in Acute Dyspnea

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Cord Blood S100B Protein Levels in Neonates Following Intrauterine Transfusions for HDFN-Associated Fetal Anemia

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