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Response of Intracranial Pressure Based on Head-of-Bed Positioning in Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to evaluate how pressure inside the skull responds to position changes in patients with brain bleeds.
The optimal positioning of the head-of-bed (HOB) has remained controversial in the neurosurgical field. Very limited data exists outlining the effects of HOB positioning in subarachnoid hemorrhage (SAH) patients. One study by Schulz-Stubner and Thiex assess the effects of HOB positioning in SAH and traumatic brain injury (TBI) patients. While this study offers some valuable insight into the changes in cerebral hemodynamics seen when the HOB changes, it congregates data from two very different pathologies. This could potentially misrepresent the true effects patients experience. A study by Kung et al. assesses cerebral blood flow dynamics and HOB changes in the setting of SAH but does not evaluate the effects on intracranial pressure (ICP) (Kung, et al., 2013). There appear to be no studies which evaluate the effect of HOB positioning on ICP in patients with SAH. No current data exists to determine if dependent leg positioning would help to further lower ICP. Theoretically, placing a patient's legs in a dependent position would lead to increased venous pooling of blood in the legs which might translate to lower ICP.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States
Start Date
April 24, 2023
Primary Completion Date
March 1, 2026
Completion Date
March 1, 2026
Last Updated
May 2, 2025
15
ESTIMATED participants
Supine
OTHER
Semi-Recumbent
OTHER
Semi-Recumbent with Legs Flexed
OTHER
Lead Sponsor
Milton S. Hershey Medical Center
NCT06119061
NCT06766422
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT05103566