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The Analgesic Efficacy of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty: | Clinical Trials | Clareo Health

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The Analgesic Efficacy of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty:

The Analgesic Efficacy and Safety of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty: A Randomized Triple-Blind Trial

NCT05602519•Al-Azhar University

View on ClinicalTrials.gov

Summary

Oxycodone showed similar or superior analgesic effects than fentanyl and was proposed as an alternative for fentanyl for pain control in the postoperative period. However, it was mainly directed to control visceral pain, due to the mediation of analgesic effects by the kappa receptors. However, few studies compared the oxycodone to fentanyl for postoperative pain relief in patients undergoing total hip arthroplasty (replacement). Therefore, we established this randomized study to compare the efficacy of oxycodone and fentanyl for relief of postoperative pain after total hip arthroplasty (replacement).

Eligibility

Age

28 - 62 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients aged 28-62 years old,
•Both genders, American Society of Anesthesiologists (ASA) physical status classification I or II who scheduled for elective total hip surgery.

Exclusion Criteria

•Patients with history of any kind of drug allergy.
•drug abuse.
•psychological or other emotional problems,
•renal and hepatic chronic disease.

Locations (1)

Facualty of Medicine (Damietta), Al Azhar University

Damietta, Egypt

Key Dates

Start Date

November 10, 2022

Primary Completion Date

May 30, 2023

Completion Date

May 30, 2023

Last Updated

August 7, 2023

Enrollment

ACTUAL participants

Conditions

Total Hip ArthroplastyThe Analgesic Efficacy

Interventions

propofol, rocuronium and fentanyl

DRUG

Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty

NCT07347821

Total Hip Arthroplasty (THA)Total Knee Arthroplasty (TKA)+2 more

View study

RECRUITINGNA

Comparing Collared and Collarless Femoral Stems in Primary Total Hip Arthroplasty

NCT07337642

Primary Total Hip Arthroplasty

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 7, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Analgesic Efficacy of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty:

Inclusion Criteria

Exclusion Criteria

Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty

Comparing Collared and Collarless Femoral Stems in Primary Total Hip Arthroplasty

Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

Effects of tDCS Combined With CBI on Postsurgical Pain

Effect of Oral Melatonin Versus Intraoperative Lidocaine Infusion on Incidence of Postoperative Delirium in Elderly Patients Undergoing Total Hip Arthroplasty

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