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A Modern Comparison of Suture Repair With Mesh Repair for Incisional Hernia
The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.
This is a patient-blinded randomized control trial comparing incisional hernia repair using synthetic mesh versus suture repair. This is a non-inferiority trial theorizing that suture repair will be non-inferior with respect to quality of life (using the HerQLes survey) at 1 year postoperatively. Patients will be blinded to the intervention, groups will be in parallel.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
University of Florida
Gainesville, Florida, United States
Northwestern
Chicago, Illinois, United States
Cleveland Clinic Main Campus
Cleveland, Ohio, United States
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
Vanderbilt University
Nashville, Tennessee, United States
Start Date
November 14, 2022
Primary Completion Date
October 1, 2026
Completion Date
October 1, 2031
Last Updated
January 7, 2026
154
ESTIMATED participants
Incisional hernia repair
PROCEDURE
Lead Sponsor
Clayton Petro
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06762561