Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Contra-indication to Sonovue (allergic reaction, uncontrolled hypertension, pulmonary hypertension, previous episode of acute coronary syndrome or documented coronary artery disease, heart failure, arythmia)
pregnancy
lactating mothers
severity of disease
presence of cyst volume of \> 25% of the total volume of the lesion
patients who decline to participate in the study
patients with contraindication to the procedure.
Patients who had received previous chemotherapy or radiotherapy.

Contrast Enhanced Harmonic Endoscopic Ultrasound (CH-EUS), Elastography, and Fractal Analysis in Predicting Pancreatic Cancer Aggressiveness and Response to Therapy.