McGill University Health Centre/Research Institute of the McGill University Health Centre
The investigators will prospectively analyze OS-CMR data from patients with a generalized anxiety disorder from one site. The investigators will observe how an anxiety disorder affects the OS-CMR data. In a follow-up MRI scan, the investigators will look at the OS-CMR of a subgroup who have anxiety disorder and are also undertaking cognitive behavioural therapy to asses how and if this therapy affects the OS-CMR data.
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Patient population:
Age 18-55,
Confirmation of an anxiety disorder as identified by the PSWQ,
No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system (except anxiety and depression)
Non-smoker
Healthy Volunteers:
Age 18-55
No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system
Non-smoker
You may not be if
General MRI contraindications: pacemakers, defibrillating wires, implanted defibrillators, intracranial aneurysm clips, metallic foreign bodies in the eyes, pregnancy
History of significant neurological disease or illness that is not anxiety (e.g. Dementia, stroke)
Hemodynamically unstable conditions
Significant or uncontrolled arrhythmias
Severe pulmonary disease
Recent (\<90 days) myocardial infarction
Recent (\<90 days) surgery or coronary intervention
Consumption of caffeine (caffeinated beverages, coffee, tea, cocoa, chocolate) within 12h of the exam
Use of benzodiazepines or other short-acting anxiety medications (\<1 day)
Clareo Health | BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
