Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder

Exclusion Criteria

• •• Patient with bipolar disorder, schizophrenia or psychotic disorder as defined by the DSM-5 and assessed by the MINI or any other pathology or treatment deemed clinically incompatible with the study by the investigator;
• •* Patient with moderate to severe substance use disorders (\>=4/11 criteria as defined in the DSM-5) and with the exception of smoking disorders
• •* Patient with pregnancy, unstable physiological condition or severe and symptomatic medical condition;
• •* Patient with a diagnosed neurological disorder affecting central nervous system function;
• •* Patient unable to give informed consent to participate in this study or unable to give the volunteer informed information;
• •* Patient who are not covered by a social security system;
• •* Patient under court protection or guardianship
• •* Patient who have received a vaccination within one month prior to initiation of treatment or who plan to be vaccinated within 2 weeks of initiation of treatment \> For patient undergoing MRI: presence of a contraindication for MRI examination.