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Active Not RecruitingPhase 3NCT05567796

A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

This study has 2 parts: First part is the main study and second part is the extension study. During the main study participants will receive 1 of 4 study medicines. If participants continue in the ext...

Lead sponsor: Novo Nordisk A/S•45 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Novo Nordisk A/S

Age

All ages

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Male or female
•Age above or equal to 18 years at the time of signing informed consent
•Body mass index (BMI) greater than or equal to 30.0 kilograms per square meter (kg/m\^2) or b) BMI greater than or equal to 27.0 kg/m\^2 with the presence of at least one weight-related comorbidity including, but not limited to hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease

Exclusion Criteria

•\- Glycaemia related: a) Glycated Haemoglobin (HbA1c) greater than or equal to 6.5 percent (48 millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening b) History of type 1 or type 2 diabetes mellitus

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 30, 2026Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhasePHASE3

Enrollment3,400

Start dateNov 2022

Last updatedMar 30, 2026

Condition

Locations shown

Univ of Alabama Birmingham

Birmingham, Alabama

Velocity Clin Res Los Angeles

Los Angeles, California

Velocity Clin Res Wstlke

Los Angeles, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 30, 2026Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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