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Acute Oral Effects of Heated Tobacco Products Compared to Traditional Cigarettes
Heated tobacco products (HTP) are devices which heat, but not burn tobacco. They do not produce cigarette smoke but rather an aerosol. HTPs are marketed as less harmful alternatives to smoking. Use and awareness of these devices have grown exponentially in recent years, with probably millions of people currently using them. There is very little literature about them, so it is quite important to study the effects caused on the human body by these products. The benefits and risks of HTP use are uncertain. There is no research on the acute oral effects of HTPs in the scientific literature.
Measurements of acute oral effects before and after using HTP with bland flavour (HEETS Bronze Selection), with methol flavour (HEETS Blue Selection), conventional cigarette and placebo device: measurement of exhaled CO changes by Smokerlyzer piCO measurement of oral mucosal blood flow changes by Perilam PSI System High Resolution (LASCA method) measurement of blood pressure and pulse by an automatic blood pressure monitor (Omron M2, Omron Healthcare Inc., Kyoto, Japan)
Age
18 - 49 years
Sex
ALL
Healthy Volunteers
Yes
Semmelweis University, Department of Prosthodontics
Budapest, Hungary
Start Date
October 1, 2021
Primary Completion Date
November 22, 2023
Completion Date
November 22, 2023
Last Updated
November 27, 2023
10
ACTUAL participants
IQOS 3.0 DOU with bland taste unit (Heated Tobacco Product)
DEVICE
IQOS 3.0 DUO with menthol taste unit (Heated Tobacco Product)
DEVICE
Marlboro Gold (Conventional cigarette)
DEVICE
IQOS 3.0 DUO turned off with a bland taste unit
DEVICE
Lead Sponsor
Semmelweis University
NCT05665465
NCT06965296
Data Source & Attribution
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