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High-field MR Imaging in Migraine, Visual Snow and Epilepsy

NCT05524493·2 sites·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lynn Farner, MSc
CONTACT
+41 44 510 72 08 lynn.farner@balgrist.ch

Lead

University of Zurich

With

Balgrist University Hospital

Age

18–65

Sex

ALL

Healthy volunteers

Accepted

You may be eligible if

Patients:
Patient must be able to read and sign the informed consent form
Stable prophylactic medication for 2 months prior to MRI
At leat one of the two criteria applies:
Patients diagnosed with migraine (with or without aura, episodic or chronic). Diagnosis is ensured by clinical interview (at least 8 weeks prior to MRI). Also, patients complete a migraine questionnaire (HARDSHIP) (at least 8 weeks before MRI). Migraine frequency ≥ 2 migraine attacks/month.
Patients with drug resistent epilepsy accroding to ILAE crtieria
Patients with diagnoses of Visual snow syndrome
Healthy participants;
No migraine (validated by questionnaire) or epilepsy
Participants must be able to read and sign the informed consent form

You may not be if

Treatment of migraine disease with Botox within \< 4 months before baseline and during the study period
Pregnant or breastfeeding women
Intention during the course of the trial to become pregnant
Women with bilateral ovariectomy, with or without hysterectomy, and postmenopausal women (\>2 years of age) are not considered childbearing.
Other clinically significant comorbidities (e.g., renal insufficiency, hepatic dysfunction, cardiovascular disease, etc.),
Known or suspected noncompliance with the protocol, drug or alcohol abuse,
Patient's inability to follow trial procedures, e.g., due to language problems, mental illness, dementia, etc.,
Prior participation in the clinical trial
Enrolment of the investigator, his/ her family members, employees and other dependent persons of the test personnel
Metallic objects in the body (e.g., splinters, MR incompatible implants).
Pacemaker
Claustrophobia
Obesity (body mass index \> 35 kg/m2)

The record

StatusRecruiting

PhaseNo phase

Taking part200

StartedMar 2025

UpdatedOct 8, 2025

Conditions

Migraine Epilepsy Visual Snow Syndrome

Where2

Klinik Lengg
Zurich, Switzerland
University Hospital Zurich
Zurich, Switzerland