Acute Plasma Abeta Responses to Stress

Inclusion Criteria

• •Healthy adult weighing at least 110 pounds
• •No chronic conditions or illness
• •Taking no medications or drugs that might alter the stress response (e.g., corticosteroids, beta-blockers, and others)
• •Not using any hormone-containing medication (e.g., hormonal contraceptives, hormone replacement, etc.)
• •No contraindications for cold pressor test exposure (high blood pressure, heart disease, dysrhythmia, peripheral vascular disease, any other cardiovascular disorder, diabetes, vasculitis, lupus, tingling or numbness in the hands and/or feet, cryoglobulinemia, and Reynaud's phenomenon)
• •No history of fainting during blood draws
• •No phobia of having their blood drawn
• •No general history of fainting or seizures
• •Not currently diagnosed with a mood disorder (e.g., major depressive disorder)
• •Not pregnant in the past 12 months
• •Not lactating in the past 12 months
• •Not trying to become pregnant if premenopausal
• •Experienced natural menopause if postmenopausal
• •Be non-smokers
• •Be fluent in English