Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

Exclusion Criteria

• •1. Pregnancy
• •2. Cirrhotic patients as per operational definition
• •3. Chronic Hepatitis B or chronic hepatitis C
• •4. Patients taking long term steroids, highly active antiretroviral therapy, diltiazem, irinotecan, oxaliplatin and amiodarone
• •5. Patients taking alcohol (based on history and AST to ALT ratio)
• •6. Patients with heart failure (NYHA Classification class III or IV status: patients comfortable at rest but less than ordinary physical activity causes undue fatigue, dyspnea or palpitations)
• •7. Patients with renal failure (serum creatinine ≥ 1.4 mg% or eGFR \< 45 ml/min/1.73 m2)